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Isothiazolinones CMIT

Isothiazolone has good efficacy in killing and stripping fungi, bacteria, algae, mollusks and slime. In the use of content, can be naturally degraded into non-toxic substances, the environment does not produce pollution.


Molecular Formula: C4H5NOS.C4H4ClNOS

Isothiazolinone - Names and Identifiers

Name:Kathon 886

Synonyms:Con WT
Kathon 886
Kathon biocide
kathon biocide
Isothiazolinone (Mit, Cmit)
5-Chloro-2-methyl-3(2H)-isothiazolone with 2-methyl-3(2H)-isothiazolone
5-Chloro-2-methyl-3(2H)-isothiazolone mixt. with 2-methyl-3(2H)-isothiazolone




Isothiazolinone - Physico-chemical Properties

Molecular Formula:C4H5NOS.C4H4ClNOS

Molar Mass:264.756

Density:d20 1.19

Boling Point:100.1℃ at 101.325kPa

Flash Point:74.9°C

Vapor Presure:0.003-17Pa at 20-45℃


PH:3.43 at 20℃ and 10g/L

Storage Condition:Sealed in dry,Room Temperature

Isothiazolinone - Risk and Safety

Toxicity:LD50 (mg/kg) orally in rabbits: 30; i.p. in male, female rats: 4.6, 4.3; LC50 (6 day) in trout, sunfish (mg/l): 0.14, 0.54; LC50 (8 day dietary) in Bobwhite quail, Peking duck (mg/kg/day): >60, >100 (J. Am. Coll. Toxicol.)

Isothiazolinone - Nature

pure as a white solid. Fp about 18 ~- 21.5 deg C; d20 1.19. 23 C viscosity (5,0±0.2) * lO-a. s. Soluble in water and low carbon alcohol, ethylene glycol and polar organic solvents. Stable at room temperature, pH 3. 5~9.5 effective. Soluble in water and lower alcohols and hydrophilic organic solvents. It can react with sodium metabisulfite (or sodium bisulfite) solution to become a non-toxic substance.

Isothiazolinone - Preparation Method

dimethyl dithiodipropionate is subjected to aminolysis reaction with methylamine to form N.N'-= methyldithiodipropionamide, and then reacted with chlorine in ethyl acetate solution, and the product is obtained by filtration, washing and drying. The ratio of the two active components in the product has a great influence on the performance of the product.

Isothiazolinone - Use

isothiazolone has good efficacy in killing and stripping fungi, bacteria, algae, mollusks and slime. In the use of content, can be naturally degraded into non-toxic substances, the environment does not produce pollution. Good miscibility, can be mixed with chlorine and other oxidizing fungicides, scale inhibitors and dispersants, most cationic surfactants, anionic surfactants and non-ionic surfactants and play a synergistic effect, and quaternary ammonium salt compound use effect is better. It can pass through the surface layer of the slime and kill the bacteria and algae in the slime, and can prevent the formation of the slime in the cooling water system. It has excellent bactericidal effect in a wide pH range and is effective in both acidic and alkaline water. Can be widely used in paper mill cooling water, oil field water injection, metal processing oil, latex, fiber and coating and other mold. However, it cannot be used in cooling water systems containing sulfide.

Isothiazolinone - Safety

rabbit oral LD50:30mg/kg; Male and female rats were intraperitoneally injected with LDso:4.6mg/kg, 4. 3 mg/kg. It is corrosive, can damage the eyes, stimulate the skin, have allergic reactions, inhalation is harmful to the human body, and may be fatal by mouth or through skin absorption, if you accidentally stick to the skin or enter the eyes need to rinse with plenty of water. Avoid inhalation of dust or vapors. Toxic to fish, do not pour into lakes, rivers, ponds or public waters. High temperature environment should be avoided during storage, and dangerous goods should be treated.

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